携带^125I粒子导管和徒手粒子植入模拟病灶后粒子纵向间距准确性的对比研究

A comparative study on the accuracy of longitudinal distance between ^125I seed implantation with degradable catheters and by hand

目的 对比携带^125I粒子的可降解导管植入和徒手粒子植入后粒子纵向间距的准确性。方法 本研究用薯蓣制成24个模拟病灶，分为徒手组和粒子导管组，每组12个模拟病灶，由3位医师完成粒子和粒子针插植，每位医师每组插植4个病灶，每组共插植60针道，并按设定粒子间距（0.5和1.0 cm）分别在两组模拟病灶内行粒子植入。术后CT复查，并测量粒子纵向间距。配对t检验分析徒手组和导管组与设定间距偏离的差异。结果 徒手组与设定间距的偏离程度分别为（0.184±0.047）和（0.127±0.051）cm，导管组与设定间距的偏离程度分别为（0.007±0.006）和（-0.003±0.006）cm，导管组粒子的偏离程度明显小于徒手组（t=3.804、2.499，P〈0.05）。结论 携带125I粒子导管的应用，使粒子纵向间距的准确性优于徒手组，受术者的影响较小。

Objective To compare the accuracy of ^125I seeds longitudinal distance between groups by degradable catheters and hand. Methods The study was divided into two groups （implantation by degradable catheters and that by hand）. There were 12 simulated lesions in each group. Seed needle and ^125I seeds were implanted by three physicians according to the set longitudinal distance （0.5 and 1.0 cm）. Postoperative CT was conducted and the longitudinal distance between seeds was measured, and then the data was analyzed between the actual distance and the designed distance in each group. Results The degree of deviation from the set distance were （0.184±0.047） and （0.127±0.051） cm in the group by hand, and （0.007±0.006） and （-0.003±0.006） cm in degradable catheters group. The degree of deviation of the seeds in the catheter group was significantly lower than the group by hand （t=3.804, 2.499, P〈0.05）. Conclusions The accuracy of the longitudinal distance of the group by catheter is much better than that by hand.