摘要
从诱导前列腺癌细胞凋亡、细胞周期阻滞、抑制癌血管生成和癌细胞转移、激活免疫等方面综述了灵芝(Ganoderma lucidum)对抑制前列腺癌的作用机理,为深入研究和开发以灵芝为来源的防治前列腺癌的功能性食品、保健品和药品提供科学依据。
Recent advances in mechanisms of the anti-prostate cancer activity of Ganoderma lucidum were reviewed. To our knowledge, multiple machanisms act in concert to deliver the anti-prostate cancer effect. These mechanisms include induction of cancer cell apotosis, blockage of cancer cell cycle, inhibition of angiogenesis and metastasis, and activation of immune system. These findings provide bases for further research and development of G. lucidum-based functional foods, health products and theraputic agents for prevention and treatment of prostate cancer.
作者
汪雯翰
贾薇
张劲松
徐宾
杨焱
王忠
张赫男
WANG Wenhan1 , JIA Wei1 , ZHANG Jingsong1 , XU Bin1 , YANG Yan1 , WANG Zhong2 ,ZHANG Henan1(1 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Resources and Utilization of Edible Fungi （South）, Ministry of Agriculture; National Engineering Research Center of Edible Fungi; National R＆D Center for Edible Fungi Processing; Key Laboratory of Agricultural Genetics and Breeding of Shanghai, Shanghai 201403, China; ZDepartment of Urology, Sixth People＇s Hospital South Campus affiliated with Shanghai Jiaotong University, Shanghai 201400, China)
出处
《食用菌学报》
CSCD
北大核心
2018年第1期107-112,共6页
Acta Edulis Fungi
基金
上海市市级农口系统青年人才成长计划[沪农青字(2016)第1-14号]和上海市科技兴农重点公关项目[沪农科攻字(2016)第5-4号]
关键词
细胞凋亡
细胞周期
雄激素受体
血管生成
转移
免疫
Cell apoptosis
cell apoptosis
cell cycle
androgen receoptor
angiogenesis
metastasis
immune
