摘要
Kinsenoside is a main active component isolated from plants of the genus Anoectochilus,and exhibits many biological activities and pharmacological effects,including hepatoprotective,anti-hyperglycemic,anti-hyperliposis,anti-inflammatory,vascular protective and anti-osteoporosis effects and so on,which is contributing to its promising potency in disease treatments.This review aims to recapitulate the pharmacological functions of kinsenoside,as well as its source,extraction,identification,quantitative analysis,pharmacokinetics,synthesis and patent information.The data reported in this work can confirm the therapeutic potential of kinsenoside and provide useful information for further new drug development.
Kinsenoside is a main active component isolated from plants of the genus Anoectochilus,and exhibits many biological activities and pharmacological effects,including hepatoprotective,anti-hyperglycemic,anti-hyperliposis,anti-inflammatory,vascular protective and anti-osteoporosis effects and so on,which is contributing to its promising potency in disease treatments.This review aims to recapitulate the pharmacological functions of kinsenoside,as well as its source,extraction,identification,quantitative analysis,pharmacokinetics,synthesis and patent information.The data reported in this work can confirm the therapeutic potential of kinsenoside and provide useful information for further new drug development.
作者
齐昌兴
周群
周渊
罗增伟
代冲
朱虎成
陈春梅
薛永波
汪建平
王亚芬
刘亚平
向明
孙伟光
张锦文
张勇慧
Chang-xing QI 1, Qun ZHOU 1, Yuan ZHOU 1, Zeng-wei LUO 1, Chong DAI 1, Hu-cheng ZHU 1, Chun-mei CHEN1, Yong-bo XUE 1, Jian-ping WANG1 , Ya-fen WANG 1, Ya-ping LIU 1, Ming XIANG 1, Wei-guang SUN 1, Jin-wen ZHANG 2, Yong-hui ZHANG(1.Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; 2.Department of Pharmacy, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 Chin)