抗磷脂抗体在具有潜在血栓风险人群中的筛查价值

Clinical screening value of antiphospholipid antibodies in potential thrombotic risk people

随着大众健康意识的提高，体检被越来越多的人们所认可，体检的目的就是为了通过检查发现是否有潜在的疾病，以及时采取预防和治疗措施。血栓性疾病是指由于血栓形成导致血管堵塞所引起的相应器官组织病变、坏死、相应功能障碍及损伤等多种疾病的总称，包含脑梗、心梗、流产等。具有高发病、高致残、高致死、高复发和发病急、恶化快，救治难等特点。绝大多数高风险者在发病前无法获得有效和准确的预警，因此发病后病情快速恶化而导致致残或猝死，而缺乏有效预警指标是以往血栓预防最严重的不足问题，所以抗磷脂抗体（antiphospholipid antibody，aPL）能够有效的预警血栓性疾病，而aPL的检测就变得越来越有意义。

With the improvement of health awareness of people, physical examination has been widely accepted by more and more people. The purpose of the physical examination is to find the underlying diseases and take preventive and curative measures. Thrombotic diseases refer to the diseases which result from pathologi- cal changes, necrosis, dysfunction and damage of organize tissue caused by thrombus, including cerebral infarc- tion, myocardial infarction, recurrent miscarriage and so on. Thrombotic diseases are characterized by high mor- bidity rate, high fatality rate and high recurrence, in other way, it occurred acutely, deteriorate rapidly and is hard to treat. The vast majority of high-risk people are unable to obtain effective and accurate early warning be- fore happening of the disease. Therefore, the rapid deterioration of the diseases cause rapid disability or sudden death. The most serious deficiency is lack of an effective warning indicator. Antiphospholipid antibodies may be an effectively warn signal of thrombotic diseases, the detection of antiphospholipid antibodies become more and more important.