血清C-反应蛋白及降钙素原对评估儿童社区获得性肺炎的作用

Role of Serum C-Reactive Protein and Procalcitonin in the Evaluation of Community-Acquired Pneumonia of Children

目的探讨血清C-反应蛋白及降钙素原在儿童社区获得性肺炎(CAP)病情评估中的作用。方法选取我院2014年6月至2017年6月期间收治的100例CAP患儿,按病情严重程度分为轻度CAP组(54例)和重度CAP组(46例),另选取同期于我院体检的50例健康儿童作为对照组。对比三组的血清C-反应蛋白和降钙素原水平。结果轻度CAP组和重度CAP组的血清C-反应蛋白和降钙素原水平均明显高于对照组(P<0.05)。重度CAP组的血清C-反应蛋白和降钙素原水平均明显高于轻度CAP组(P<0.05)。结论 CAP患儿的血清C-反应蛋白和降钙素原水平均明显升高,血清C-反应蛋白及降钙素原可有效评估儿童CAP的病情严重程度。

Objective To explore the role of serum C-reactive protein and procalcitonin in the evaluation of community-acquired pneumonia （CAP） of children. Methods 100 cases of children with community-acquired pneumonia admitted to our hospital from June 2014 to June 2017 were selected and divided into mild CAP group （54 cases） and severe CAP group （46 cases） according to the severity of disease. Another 50 healthy children undergoing physical examination in our hospital during the same period were selected as the control group. The serum C-reactive protein and procalcitonin levels were compared among the three group. Results The serum C-reactive protein and procalcitonin levels of the mild CAP group and severe CAP group were significantly higher than those of the control group （P 〈0.05）. The serum C-reactive protein and procalcitonin levels of the severe CAP group were significantly higher than those of the mild CAP group （P 〈0.05）. Conclusions The serum C-reactive protein and procalcitonin levels of CAP children significantly increase, and the serum C-reactive protein and procalcitonin can effectively evaluate the CAP severity of children.