湖北省恩施州不同硒水平环境居民血硒、指甲硒调查

Investigation on Blood and Nail Selenium of Residents in Environment with Different Selenium Levels in Enshi,Hubei Province

目的调查研究恩施州不同硒水平环境人群血硒、指甲硒水平,反映常住居民生物硒吸收利用效果。方法在恩施州极高硒环境区、高硒环境区、足硒环境区、缺硒环境区,四个不同硒水平环境类型区域各随机选取3个调查点进行人群血硒、指甲硒含量调查研究,同时对调查点的基本情况进行问卷调查并采集部分当地原产农作物进行硒含量测定。结果恩施州不同硒水平环境人群血硒、指甲硒含量平均值和环境硒水平有明显的一致性,从缺硒区到极高硒区人群血硒、指甲硒含量依次上升。各年龄组血硒、指甲硒浓度年龄分布呈现从缺硒区到极高硒区梯度上升现象,并有统计学意义。不同硒水平环境人群指甲硒含量与血硒水平呈正相关,有显著性统计学意义(相关系数r=0.719,双侧Pearson检验P<0.01)。恩施州足硒区以上的原产主要农作物品种硒含量明显高于缺硒区地区,具有统计学差异。结论恩施州足硒区及以上区域人群硒摄入水平非常适宜。极高硒环境人群硒中毒危险因素基本消除。低硒环境区域人群硒摄入水平有了明显改善,但尚未达到最佳硒营养状态。指甲硒也是机体硒营养水平良好的检测指标。

Objectives To investigate the level of selenium in blood and nail samples in Enshi with different concentration of selenium in the environment to reflect the absorption and utilization of bio-selenium in local resi- dents. Methods The blood and nail selenium level of residents living in three sites of each four areas with differ- ent levels of selenium（ extreme high, high, sufficient and poor selenium） in the environment were examined. Local crops were collected for selenium determination at the same time. Questionnaire was used for the survey of basic sit- uation. Results The average selenium level inblood and nail was consistent with the trend of selenium in the envi- ronment from selenium deficiency to extreme high level of selenium, and a gradient ascent trend of blood and nail selenium with the age was observed. There was a significant correlation between nail selenium and blood selenium level with different selenium level in crops （correlation coefficient r = 0. 719, bilateral Pearson test P 〈 0.01 ）. The selenium content of main crop varietiesin the extreme high, high selenium areas in Enshi was significantly high- er than that in poor selenium area. Conclusions The selenium intake in selenium sufficient area and above in En- shi was reasonable, because risk factors for selenium poisoning in extreme high selenium areas had been basically e-liminated. There was a significant status had not been reached yet. nutrition improvement on selenium intake in poor Selenium level in nail sample was also a selenium areas, but an optimal selenium good indicator for the status of selenium