和肽素与急性心肌梗死合并新发心房颤动的关系分析

Analysis of relationship between copeptin and first-episode atrial fibrillation in patients with acute myocardial infarction

目的探讨和肽素与急性心肌梗死合并新发心房颤动的关系。方法选取本院于2016年1月至2017年4月所收治的129例急性心肌梗死患者，依心律情况分为心房颤动组和非心房颤动组，观察并比较两组患者一般资料及和肽素水平。结果心房颤动组患者和肽素水平较非心房颤动组明显更高[（21．5±3．6）pmol／L比（9．±2．3）pmol／L，P〈0．05]；行多因素Logistic回归分析表明，心率、和肽素及左心房内径是预测急性心肌梗死新发心房颤动的高危因素。结论和肽素与急性心肌梗死合并新发心颤动之间存在密切关系，可作为预测急性心肌梗死后新发心房颤动的重要指标。

Objective To investigate the relationship between copeptin and first-episode atrial fibrillation in patients with acute myocardial infarction. Methods A total of 129 patients with acute myocardial infarction in our hospital from January 2016 to April 2017 were divided into atrial fibrillation group and non atrial fibrillation group. Observed and compared general information and the level of copeptin of the two groups. Results The level of copeptin of the atrial fibrillation group was significantly higher than that of the non atrial fibrillation group [（21.5±3.6） pmol/L vs.（9.7±2.3） pmol/L, P〈0.05]. Multivariate Logistic regression analysis showed that heart rate, the level of copeptin, and left atrial diameter were the risk factors of first-episode atrial fibrillation in patients with acute myocardial infarction. Conclusion There is a close relationship between the level of copeptin and first- episode atrial fibrillation in patients with acute myocardial infarction, which can be used as an important index to predict the occurrence of first-episode atrial fibrillation in patients with acute myocardial infarction.