茶叶多糖的药理活性研究进展

Research progress on pharmacological activities of polysaccharides prepared from tea

茶叶多糖是茶叶中具有生物学活性的复合多糖的简称,其降血糖及防治糖尿病功效最为突出。茶叶多糖可通过保护胰岛β细胞、抑制外源碳水化合物的吸收和调控内源因素(糖代谢酶类和胰岛素)等三条路径来实现降血糖及防治糖尿病的表达。本文从茶叶多糖的其他生物学活性,诸如抗氧化、免疫调节、抗肿瘤、抗凝血、抗疲劳、抑菌杀毒、减肥等方面,阐述近年来茶叶多糖的药理活性及作用机理,以期为进一步研究提供依据。

Tea polysaccharides, short for polysaccharide conjugates with bioactivity in tea, have exhibited the well-known hypoglycemic effects and antidiabetic activity, due to its protection of islet β cell, restriction of carbonhydrate absorption and regulation of endogenous factors （ glucose metabolizing enzyme and insulin ） . Furthermore, the paper summarizes research progress on the other pharmacological activities and mechanism of actions of polysaccharide prepared from tea （ Camellia sinensis）. Various pharmacological activities, including antioxidant activity, immunostimulating activity, antitumor activity, anticoagulant activity,anti-fatigue activity,antibacterial and antiviral activity,and anti-obesity activity are described for the further study.