摘要
雄激素剥夺治疗(ADT)是晚期前列腺癌的主要治疗方法。虽然ADT可显著延长患者的总生存期,但有时亦会对机体代谢造成严重影响。本文总结了ADT对身体构成、血脂及血糖水平、心血管系统等方面的不良影响,并对ADT代谢并发症干预管理的重要性进行论述。
Androgen deprivation therapy （ADT） is one of the dominant treatment options for advanced prostate cancer, which has been certified to significantly improve the overall survival of prostate cancer patients. However, it sometimes can also produce se- vere adverse effects on body metabolism. This review summarizes the adverse effects of ADT on body composition, the levels of choles- terol and blood glucose, and the cardiovascular system, and the intervention management of these metabolic complications as well.
作者
胡永慧
吴松
张蒙
HU Yong-hui1 , WU Song2, ZHANG Meng3(1. Department of Endocrinology, The Second Hospital of Tianfin Medical University, Tianfin 300211, China; 2. Department of Urology, Shenzhen Luohu People＇s Hospital, Shenzhen Following Precision Medical Research Insti- tute, Shenzhen, Guangdong 518001 , China ; 3. Department of Urology, The First Affiliated Hospital of Anhui Medi- cal University, Hefei, Anhui 230031, Chin)
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2018年第3期277-281,共5页
National Journal of Andrology
基金
广东省自然科学基金(2017A030313800)~~
关键词
前列腺癌
雄激素剥夺治疗
代谢并发症
干预管理
prostate cancer
androgen deprivation therapy
metabolic complication
intervention management
