摘要
介绍了右佐匹克隆中间体在制备过程中产生的4个关键杂质的合成方法,且所合成的化合物结构经HPLC、HRMS和NMR确证。
The method for the preparation of four key impurities in Eszopiclone intermediates was described.These four impuritities were synthesized and their structure were confirmed by HPLC, HRMS, and NMR.
作者
俞育庆
盛力
范钢
沈大冬
YU Yu-qing;SHENG Li;FAN Gang;SHEN Da-dong(Zhejiang Medicine CO., LTD., Xinchang Pharmaceutical Factory, Xinchang 312500, China)
出处
《精细化工中间体》
CAS
2017年第5期35-37,48,共4页
Fine Chemical Intermediates
关键词
右佐匹克隆
杂质合成
结构鉴定
eszopiclone
impurities synthesis
structure identification