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EB病毒编码microRNAs生物学功能的研究进展 被引量：2

Research advances in biological function of Epstein–Barr virus encoded microRNAs
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摘要 研究表明EB病毒作为人类主要的致癌病毒,可通过编码mi RNAs参与病毒感染、细胞凋亡、肿瘤侵袭与转移等过程。本文综述了EBV miRNAs的合成及作用机制,旨在为EB病毒相关疾病研究提供新的信息。 Numerous studies have demonstrated that Epstein-Barr virus, a vital carcinogenic virus of human cancer, is involved in viral infection, apoptosis, tumor invasion and metastasis through coding microRNA （miRNA）. In this review, we summarize the synthesis of EBV encoded miRNAs and their functional mechanisms, which may provide new target and strategies for the treatment of EB virus related diseases.
作者 陈美慧 李晶 胡文佳 黄辉 陈晨 周克元 李祥勇 CHEN Meihui, LI Jing, HU Wenjia, HUANG Hui, CHEN Chen, ZHOU Keyuan, LI Xiangyong(Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Zhanjiang 524023, Guangdong Province, China)
机构地区 广东医科大学生物化学与分子生物学研究所
出处 《解放军医学院学报》 CAS 2018年第3期255-258,共4页 Academic Journal of Chinese PLA Medical School
基金 国家自然科学基金项目(81272434) 广东省医学分子诊断重点实验室开放课题项目(FZZD201605)~~
关键词 EB病毒 MICRORNA 肿瘤 Epstein-Barr virus microRNA tumor
分类号 R373 [医药卫生—病原生物学]
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解放军医学院学报
2018年 第3期

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