摘要
对紫苏的化学成分进行研究.采用75%乙醇提取紫苏,提取物通过大孔吸附树脂、硅胶柱色谱、ODS柱色谱进行分离,进一步应用半制备高效液相色谱进行纯化,应用核磁共振技术并参照相关文献对得到化学成分进行结构确定.共分离得到了5个化合物,分别为5-methoxyisolariciresinol、syringaresinol mono-β-D-glucoside、lyoniresinol、patrinalloside、patrinoside-aglucone.所有化合物均为首次从该植物中分离得到.
To study the chemical constituents of Perilla frutescens(L.) Britt. 75% Et OH extract of Perilla frutescens(L.) Britt. was separated by macroporous resin,normal phase chromatography,ODS and RP-HPLC to isolate natural compounds. And their structures were elucidated by NMR spectral analysis and the references. Five compounds were isolated from the plant,and all the compounds were identified as 5-methoxyisolariciresinol,syringaresinol mono-β-D-glucoside,lyoniresinol,patrinalloside,patrinoside-aglucone. All the compounds were isolated from the plant for the first time.
作者
叶宇
梁克利
YE Yu1 , LIANG Ke-li2(1.First Affiliated Hospital of Dalian Medical University, Dalian 116600, 2. Jian An Pharmaceutical Ltd, Shenzhen 518027, Chin)
出处
《哈尔滨商业大学学报(自然科学版)》
CAS
2017年第5期523-525,共3页
Journal of Harbin University of Commerce:Natural Sciences Edition
关键词
紫苏
化学成分
结构鉴定
PeriUa frutescens ( L. ) Britt
chemical constituents
structural identification