住院时间对精神分裂症患者出院后1年内再入院的影响

An analysis of hospital stay and readmissions within 1 year after dischargein patients with schizophrenia

目的探索住院时间对精神分裂症住院患者出院后1年内再入院的影响。方法选取441例出院精神分裂症患者,调查1年内的再入院情况,收集患者的住院天数、人口学特征、疾病特征及服药依从性等,以平均住院天数65 d为界,将患者分为两组,采用Kaplan-Meier生存分析比较两组之间再入院风险的差异,再以患者的人口学特征、疾病特征、服药依从性为协变量,采用COX回归分析住院时间是否作为独立的因素影响患者再入院的发生。结果 Kaplan-Meier生存分析显示,住院时间长的患者再入院的风险高于住院时间短的患者(P<0.05),COX回归分析发现,排除混杂因素的影响后,住院时间不再是精神分裂症患者1年内再入院的影响因素(P>0.05)。结论排除混杂因素影响后,暂时未发现住院时间对精神分裂症患者出院后1年内的再入院产生影响。

Objective To explore the relationship between hospital stay and readmissions within 1 year after discharge in patients with schizophrenia. Methods A total of 441 patients with schizophrenia were selected and divided into two groups according to 65-day of average hospitalization. They were assessed with the general information, the status of readmissions within 1 year and so on. Results The results of Kaplan-Meier Survival Analysisshowed that the risk of readmissionsin patients with long hospital staywas significantly higher than that in patients with short hospital stay （ P 〈 0.05 ）. The results of COX proportional- hazards regression analysisshowed that there was no relationship between hospital stay and readmissions within 1 year after discharge in patients with schizophrenia（ P 〈 0.05 ） without the impacts of the confounding factors. Conclusions There is no relationship between the hospital stay and readmissions within 1 year after discharge in the patients with schizophrenia.