补脑息风止痉汤治疗帕金森病的临床观察

Clinical Observation on Bunao Xifeng Zhijing Decoction in the Treatment of Parkinson's disease

目的探究补脑息风止痉汤治疗帕金森病的临床疗效。方法选取帕金森病患者60例随机分为2组,各30例。对照组患者予以美多巴(左旋多巴200 mg,苄丝肼50 mg),日1次;试验组在此基础上给予补脑息风止痉汤,日1剂水煎服,2组均治疗2个月。治疗前后比较2组患者临床疗效,UPDRS评分及安全性。结果治疗后2组UPDRS-1、UPDRS-2以及UPDRS-3评分降低(P<0.05),与对照组相比,试验组临床总有效率较高,UPDRS-1、UPDRS-2以及UPDRS-3评分较低(P<0.05),2组不良反应发生率相比无明显差异(P>0.05)。结论补脑息风止痉汤对帕金森病患者临床疗效显著,且安全性较高。

Objective To explore the clinical effect of Bunao Xifeng Zhijing decoction in the treatment of Parkinson＇s disease.Methods 60 cases of patients with Parkinson＇s disease in our hospital were randomly divided into 2 groups, with 30 cases in each group. The control group received Madopar（levodopa 200 mg, Benserazide50 mg）, qd, and the experimental group received more with Bunao Xifeng Zhijing decoction, qd. 2 groups were treated for 2 months. The clinical efficacy, UPDRS score and safety of the 2 groups were compared before and after treatment. Results Scores of UPDRS-1, UPDRS-2 and UPDRS-3 in 2 groups decreased after treatment（P〈0.05）, and comparing with the control group, the clinical total efficiency of the experimental group was higher, scores of UPDRS-1, UPDRS-2 and UPDRS-3 of the experimental group were lower（P〈0.05）, and the adverse reactions in 2 groups had no significant difference（P〈0.05）. Conclusion Bunao Xifeng Zhijing decoction has significantly clinical curative effect in treating Parkinson＇s disease and high safety.