吸烟与高密度脂蛋白胆固醇的关系

The Relationship between Smoking and High Density Lipoprotein Cholesterol

探讨吸烟与高密度脂蛋白胆固醇（ＨＤＬ－Ｃｈ）的关系。测定３７８人的ＨＤＬ－Ｃｈ，其中吸烟者１５３人，不吸烟者２２５人，按职业的不同，分别比较吸烟与不吸烟者ＨＤＬ－Ｃｈ的差异。发现：各组吸烟者的ＨＤＬ－Ｃｈ均低于不吸烟者，而致动脉粥样硬化指数则正相反；按吸烟的数量分析，除农民组外，吸烟＞２０支／ｄ比吸烟＜２０支／ｄ者的ＨＤＬ－Ｃｈ低。ＨＤＬ－Ｃｈ浓度和吸烟的关系与ＨＤＬ－Ｃｈ和冠心病的关系相似。可以认为吸烟能导致冠心病的发生。

The relationship between smoking and high density lipoprotein cholesterol (HDL Ch) has been reported.The HDL Ch of 378 subjects,including 153 smokers and 225 non smokers were determined.All subjects were divided into three groups according to their different occupations.The HDL Ch of them was studied comparatively. The results showed that the HDL Ch of smokers is lower than that of non smokers in each group whereas the arteriosclerosis index is the opposite;that the HDL Ch of the people smoking more than 20 cigarettes everyday is lower than that of those smoking less than 20 except the group of peasants. The relationship between the concentration of HDL Ch and smoking is similiar to that between the concentration of HDL Ch and coronary heart disease (CHD).It is suggested that smoking decreases HDL Ch is one of the causes of CHD.