Alzheimer型老年性痴呆病的事件相关电位

Event related Potential in Alzheimer Dementia

报告２１例Ａｌｚｈｅｉｍｅｒ型老年性痴呆ＥＲＰ检测，并以２０个正常人的ＥＲＰ检测作对照。结果：两组靶刺激的反应选择、注意相关的Ｎ１、Ｐ２波比较，病人组较对照组明显延长，有显著性差异（Ｐ＜０．０５）；与认知功能相关的Ｎ２和Ｐ３波比较，病人组较正常组亦明显延长，有非常显著性差异（Ｐ＜０．０１）。认为：ＥＲＰ检测对Ａｌｚｈｅｉｍｅｒ型老年性痴呆有临床实用价值，可以广泛应用。

Event related potentials(ERP)of 21 patients with Alzheimer dementia Were reported. The ERP components were recorded and compared with 20 normal subjects. The related N 1 and P 2 waves in the patients group were prolonged remarkably and significant difference ( P < 0.05 ) existed between the two groups. So were the N 2 and P 3 waves associated with cognitive function ( P <0.01).These results suggest that ERP may have certain clinical significance and be popularized for the diagnosis of Alzheimer dementia.