经皮冠状动脉介入术后消化道出血的原因与防治

Causes,prevention and treatment of postoperative gastrointestinal bleeding after percutaneous coronary intervention

消化道出血是经皮冠状动脉介入(PCI)的严重并发症之一,特别是消化道出血常伴随不良心脏事件的发生,引起缺血与出血的失衡,导致病死率增加,严重影响患者的临床净获益。因此,在双联抗血小板的基础上合理优化抗栓方案,对PCI术后消化道出血进行有针对性的防治显得十分重要。本文从PCI术后双联抗血小板治疗的必要性及引发出血的机制、缺血与出血的平衡、PCI术后消化道出血的预防和治疗策略等方面逐一进行阐述。

Gastrointestinal bleeding is a major severe adverse event after percutaneous coronary intervention （PCI）. When accompanied with other adverse cardiac events, it induces the imbalance between hemorrhage and ischemia and increases the risk of death. It is vital to have a targeted, strategic treatment scheme to avoid and prevent PCI postoperative gastrointestinal bleeding during dual antiplatelet and antithrombotic therapy. This paper reviewed the causes of PCI postoperative gastrointestinal bleeding and prevented in-depth elaboration on rational preventive and treatment strategies.