华蟹甲中1个新的酚苷类化合物

A new phenolic glycoside from rhizomes of Sinacalia tangutica

目的研究华蟹甲Sinacalia tangutica根茎的化学成分。方法采用大孔树脂、硅胶及反相ODS柱色谱等方法进行分离和纯化,并综合运用~1H-NMR、^(13)C-NMR、DEPT、HSQC、HMBC和HR-ESI-MS等方法鉴定化合物的结构。结果从华蟹甲乙醇提取物正丁醇萃取部分分离得到1个新的酚苷,鉴定为5-羟基丁香酚-4-O-β-D-木糖基-(1→6)-O-β-D-葡萄糖苷(1)。结论化合物1为新化合物,命名为华蟹甲苷。

Objective To study the chemical constituents from the rhizomes of Sinacalia tangutica. Methods The compounds were separated and purified by D101 macroporous resin, silica gel, and ODS column chromatography. Their structures were elucidated by extensive spectroscopic methods including ~1H-NMR, ^（13）C-NMR, DEPT, HSQC, HMBC, and HR-ESI-MS. Results One new phenolic glycoside was isolated from S. tangutica, and identified as 5-hydroxyeugenol-4-O-β-D-xylopyranosyl-（1→6）-O-β-D-glucopyranoside（1）. Conclusion Compound 1 is a new compound named singuticoside.