摘要
涎腺腺样囊性癌是发生于涎腺的一种非常常见的恶性肿瘤,其重要特质是嗜神经侵袭,这一特质是其在临床手术中很难被彻底切除的重要原因之一;部分肿瘤细胞的残留易导致肿瘤术后复发,成为临床治疗的一大难题。因此,深入探讨涎腺腺样囊性癌嗜神经侵袭这一特性的分子机制对克服这一难题具有重要意义,本文就涎腺腺样囊性癌嗜神经侵袭分子机制的研究进展作一综述。
Salivary adenoid cystic carcinoma is a very common malignant neoplasm in the salivary glands. One of the most important features of salivary cystic carcinoma is perineural invasion, which renders its complete removal is very difficult through clinical surgery. Consequently, tumor recurrence occurs easily after clinical surgery. Therefore, the molecular mechanisms of perineural invasion in salivary adenoid cystic carcinoma are necessary to explore. These mechanisms are reviewed in this paper.
作者
张美
梁新华
汤亚玲
Zhang Mei1, Liang Xinhua2, Tang Yaling1(1. State Key Laboratory of Oral Diseases ＆ National Clinical Research Center for Oral Diseases ＆ Dept. of Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China; 2. State Key Laboratory of Oral Diseases ＆ National Clinical Research Center for Oral Diseases ＆ Dept. of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Chin)
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2018年第2期204-211,共8页
West China Journal of Stomatology
基金
国家自然科学基金(81772891)
关键词
涎腺
腺样囊性癌
嗜神经侵袭
分子机制
salivary gland
adenoid cystic carcinoma
perineural invasion
molecular mechanism
