参麦荣心汤治疗慢性心力衰竭临床观察

目的:观察参麦荣心汤治疗慢性心力衰竭的临床疗效。方法:120例随机分为治疗组60例和对照组60例。对照组给予西药常规治疗,治疗组用参麦荣心汤口服,8周后观察临床疗效、心功能变化、血浆中BNP含量。结果:总有效率治疗组96.67%、对照组86.67%,两组比较差异有统计学意义(P<0.05)。两组治疗后心功能指标LVESV与LVEDV均降低(P<0.05),LVEF与LVSV指标均升高(P<0.01),且治疗组改善程度优于对照组(P<0.05)。两组血浆中BNP浓度治疗后均下降(P<0.05),治疗组优于对照组(P<0.05)。结论:参麦荣心汤治疗慢性心力衰竭可改善心功能,降低血浆BNP水平。

Objective ： To investigate the clinical effect of combination of TCM and western medicine in the treatment of chronic heart failure. Method： 120 patients with chronic heart failure were randomly divided into treatment group （n=60） and control group （ n=60 ） .Both groups were treated with routine treatment of western medicine and the treatment group were treated with Shenmai Rongxin Decoction by oral administration. After 8 weeks, the clinical therapeutic effect, changes in cardiac function, plasma BNP content was observed. Result ： The total effective rate of treatment group was 96.67% while that of the control group was 86.67% . There was significant difference between the two groups （ P〈0.05 ） .After treatment, the cardiac function index LVESV and LVEDV of both groups decreased （ P〈0.05 ） , LVEF and LVSV increased （ P〈0.01 ） and the improvement of treatment group was superior to that of the control group （ P〈0.05 ） .The plasma BNP concentration in both groups after treatment was significantly lower than that before treatment （P〈0.05） and that of the treatment group was superior to that of the control group （P〈0.05） .Conclusion： The combination of Shenmai Rongxin Decoction and conventional western medicine could significantly improve the cardiac function and reduce the plasma BNP level.