基于光声技术的血糖无损检测

Blood Glucose Noninvasive Measurement Based on Photoacoustic Technique

血糖无损检测技术已经成为生物医疗领域研究的一大热点,光声技术基于组织内部的光学吸收差异性,以超声作为媒介进行血糖检测,从原理上避开了组织对光学强散射的干扰,为血糖无损检测提供了一种高灵敏度的测量手段。对近年来血糖光声无损检测技术的发展进行了综述分析,首先简要介绍了血糖光声检测的原理,然后重点对国内外血糖光声检测系统按照激励源的不同进行分类介绍,归纳了血糖光声检测的实验进展,以促进国内血糖无损检测技术的发展。

Noninvasive blood glucose measurement has become a research hot-spot in biomedical field. Photoacoustic technique is an ultrasound-mediated blood glucose measuring method based on the intrinsic optical absorption properties of tissue, and the technique avoids the interference of high optical scattering in principle and provides a noninvasive and effective way with high sensitivity for the noninvasive blood glucose measurement. This paper reviews the development of the noninvasive blood glucose measurement. Firstly, the principle of blood glucose photoacoustic noninvasive measurement is introduced. Then, the blood glucose photoacoustic detection systems in the domestic and foreign are introduced according to the different excitation sources and the experimental progresses in blood glucose photoacoustic detection are summarized to promote the development of domestic blood glucose noninvasive measurement technique,