基于2013-2015年无偿献血者抗-HCV筛查情况估算深圳市宝安区一般人群抗-HCV阳性率

Anti-HCV prevalence in general population in Baoan district of Shenzhen,2013-2015

目的了解深圳市宝安区2013-2015年无偿献血者丙型肝炎病毒(HCV)感染流行情况,据此估算宝安区一般人群抗-HCV阳性率。方法收集宝安区中心血站2013-2015年无偿献血者一般人口学特征、抗-HCV检测结果资料,对无偿献血者HCV感染流行情况进行统计分析,采用"比率法"基于无偿献血者抗-HCV阳性率估算一般人群抗-HCV阳性率。结果 2013-2015年无偿献血者抗-HCV筛查分别为30 150、30 771和30 276人,抗-HCV阳性率分别为0.33%、0.26%和0.28%。不同性别、年龄、年份阳性率比较差异无统计学意义(P>0.05)。据此估算宝安区一般人群抗-HCV阳性率范围为0.36%~1.12%或0.36%~0.62%。结论基于无偿献血者抗-HCV阳性率估算的宝安区一般人群抗-HCV阳性率表明宝安区为丙肝感染低流行区。

Objective To investigate the prevalence of anti-HCV among blood donors in Baoan district from 2013 to 2015, and estimate the prevalence of anti-HCV in general population of this region based on the data obtained from blood donors. Methods Information on the demographics and test results of the anti-HCV were collected. Chi-squared test was used to compare the positive rates of anti-HCV across different groups. The prevalence of anti-HCV in general population was estimated based on such information by using the ratio method. Results Between 2013 to 2015, the number of positive for anti-HCV in blood donors was 30 150, 30 771 and 30 276, respectively, with the corresponding positive rates of 0.33%, 0.26% and 0.28%, respectively. The difference of anti-HCV positive rate showed in sex, age and different years had no statistically significant （P〉0.05）. It was estimated that the positive rate of anti-HCV in general population of Baoan district ranged from 0.36% to 1.12% or 0.36% to 0.62%. Conclusion The prevalence of anti-HCV among general popula- tion estimated by blood donors suggests that Baoan district was low prevalence area of HCV infection.