阿尔茨海默病患者生活质量影响因素分析

Influencing factor analysis of quality of life of Alzheimer's disease patients

目的探究影响阿尔茨海默病患者生活质量的危险因素。方法选取本院收治的80例阿尔茨海默病患者作为阿尔茨海默病组,另外选取86例正常老年人作为对照组。所有研究对象的生活质量采用生活质量量表进行评价。采用logistic回归分析方法,分析年龄、性别等7个因素与阿尔茨海默病患者生活质量关系。结果阿尔茨海默病组患者QOL-AD的13项内容评分及总评分均低于相应的对照组,差异有统计学意义(P<0.01)。多元logistic回归分析结果显示,年龄(≥75岁)(OR=2.169)和婚姻状况无配偶(OR=2.037)是阿尔茨海默病患者生活质量降低的危险因素(P<0.05),而照顾者为配偶(OR=0.362)、子女(OR=0.4341)、保姆(OR=0.912)、其他人(OR=0.992)是阿尔茨海默病患者生活质量降低的保护性因素(P<0.05)。结论给予高龄患者更多的关注,尽量给予患者来自家庭的照顾,能够有效提高阿尔茨海默病患者的生活质量。

Objective To explore the influencing factors of quality of life of Alzheimer＇s disease patients. Methods Eighty Alzheimer＇s disease patients admitted in this hospital were selected as Alzheimer＇s disease group and 86 healthy old people were selected as the control group. The quality of life-alzheimer＇s disease （QOL-AD） was used to evaluate quality of life of all the subjects. The logistic analysis was used to analyze the relationship between quality of life of Alzheimer＇s disease patients and 7 factors including age, sex and so on. Results The grade of QOL-AD＇s 13 items and total grade of Alzheimer＇s disease group were all lower than those of the control group, with significant difference （P〈0.01）. The binary logistic regression analysis showed age （≥75years） （OR=2. 169） and being matelss （OR= 2. 037） were the risk factors of Alzheimer＇s disease patients （ P〈0.05）, and caregivers （spouse） （ OR = 0.362） was the protective factor （P〈0.05）. Conclusion More attention to elderly patients and care from their family can improve the quality of life of Alzheimer＇s disease patients effectively.