云南墨江县新生儿弓形虫血清流行病学调查

Seroepidemiological investigation of Toxoplasma gondii in Mojiang County,Yunnan Province

目的调查墨江县新生儿弓形虫感染情况,为治疗和防控弓形虫病提供参考。方法 2016年10月至2017年4月采集墨江县人民医院接生的新生儿脐血311份,应用酶联免疫吸附试验(ELISA)检测血清中弓形虫Ig G抗体。结果 311份新生儿脐血血清弓形虫Ig G抗体总阳性率为17.36%(54/311),其中哈尼族、汉族、彝族、拉祜族、其他少数民族弓形虫Ig G抗体阳性率分别为17.01%(33/194)、18.05%(13/72)、15.00%(3/20)、25.00%(2/8)、17.65%(3/17)。不同民族、新生儿性别、孕妇年龄、妊娠结局之间弓形虫Ig G抗体血清阳性率差异无统计学意义(P>0.05)。结论墨江县少数民族地区新生儿弓形虫Ig G抗体阳性率较高,应加强弓形虫病的防控健康教育。

Objective To investigate the infection status of T. gondii in neonatal in minority nationality areas of Mojiang County and analyze the risk factors so as to provide a reference for the prevention and control of toxoplasmosis. Methods 311 neonatal cord blood were collected from Mojiang County People ＇s Hospital from October 2016 to April 2017. Anti-Toxoplasma antibody（ Ig G） was detected by enzyme-linked immunosorbent assay（ ELISA）. Results The overall prevalence of T. gondii was 17.36%（ 54/311） in neonatal of Mojiang. The results indicated that Hani,Han,Yi,Lahu and other minorities were 17. 01%（ 33/194）,18. 05%（ 13/72）,15.00%（ 3/20）,25. 00%（ 2/8） and 17. 65%（ 3/17）,respectively. There was no statistical significance between different ethnic groups, fetal ＇ s sex, pregnant women ＇ s age and pregnancy history（ P 〉0. 05）.Conclusions The positive rate of Ig G antibody of T. gondii is higher in the minority nationality areas of Mojiang county.Prevention and control education of T. gondii should be strengthen in this area.