核磁共振动态增强技术用于检测青年人乳腺浸润性导管癌的影像学特征分析

Analysis of imaging features of dynamic contrastenhanced MRI in the detection of invasive ductal carcinoma of breast cancer

目的探讨核磁共振（MRI）动态增强技术对青年人乳腺浸润性导管癌的影像学特征及诊断价值。方法选取乳腺导管癌手术治疗患者75例，根据年龄分为青年组（≤40岁）22例和中老年组（〉40岁）53例，分析两组患者病变形态、位置、大小、边界、边缘有无分叶及毛刺、时间信号强度曲线（Time signal intensity Curve，TIC）情况。结果青年组非肿块型乳腺浸润性导管癌患者占54．55％，高于老年组的30．19％，差异有统计学意义（χ^2=3．94，P=0．04）。青年组乳腺浸润性导管癌边界不清楚的比例为63．64％，高于老年组的37．74％，差异有统计学意义（χ^2=4．21，P=0．04）。青年组乳腺浸润性导管癌病灶分叶的比例为59．09％，老年组为62．26％，差异无统计学意义（χ^2=2．19，P=0．14）。青年组乳腺浸润性导管癌病灶边缘光滑的比例为63．64％，老年组为54．72％，差异无统计学意义（χ^2=2．26，P=0．13）。青年组乳腺导管癌TIC比较Ⅰ、Ⅱ、Ⅲ型患者分别为0、14、8例，老年组分别为0、36、17例，两组患者TIC分级差异无统计学意义（χ^2=0．13，P=0．72）。结论青年乳腺浸润型导管癌患者多为非肿块型，肿瘤边界不清；MRI动态增强技术用于检测乳腺浸润型导管癌能够减少漏诊误诊情况。

Objective To investigate the imaging features of MRI in patients with invasive ductal carcinoma of breast cancer. Methods 75 patients with breast duetal carcinoma treated by surgical treatment were selected. According to the age,75 patients were divided into young group （ ≤ 40 years） with 22 eases and elderly group （ 〉 40 years） with 53 cases. The morphology, location, size, border and edge of the two groups were analyzed. The time signal intensity curve （ TIC ） was analyzed. Results The proportion of patients with non - luminal invasive ductal carcinoma of the young group was 54.55% ,which was higher than 30.19% of the elderly group,the difference was statistically significant（ χ^2 = 3.94, P = 0. 047 ）. The proportion of breast cancer infiltrating ductal carcinoma in the young grpup was 63.64% ,which was higher than 37.74% in the elderly group,the difference was statistically significant（ χ^2 =4.21 ,P =0. 040）. The proportion of the infarcted ductal carcinoma in the young group was 59.09%, and that in the elderly group was 62. 26%, the difference was not statistically significant （χ^2 = 2. 19 ,P = 0. 14）. The proportion of breast invasive ductal carcinoma in the young group was 63.64% , which in the elderly group was 54.72%, the difference was not statistically significant （ χ^2 = 0. 13, P = 0.72） I ,II and III type of breast duetal carcinoma TIC in the young group were 0eases, 14cases, 8cases, respectively, which in the elderly group were Ocases,36cases, 17 cases, respectively,there was no statistically significant difference in TIC grade between the two groups （χ^2 = 2.26, P = 0. 13 ）. Conclusion Breast infiltrating duetal carcinoma is mostly pulmonary lump type, tumor border is unclear;MRI dynamic enhancement technique for the detection of breast invasive ductal carcinoma can reduce misdiagnosis.