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骨髓间充质干细胞及其来源的微泡对慢性肾脏病修复作用的研究进展

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摘要 肾小管间质的急、慢性炎症和纤维化是导致慢性肾脏病(CKD)进展的主要病理基础。近年来研究发现,骨髓间充质干细胞(MSCs)在肾损伤修复中的作用至关重要,MSCs移植虽然促进了肾损伤修复,但并未检测到移植的MSCs分化为肾脏固有细胞,提示MSCs可能是通过旁分泌作用促进肾损伤修复。本文将围绕MSCs及其来源的微泡对CKD修复作用的研究进展进行综述。
出处 《江苏医药》 CAS 2018年第3期327-330,共4页 Jiangsu Medical Journal
基金 国家自然科学基金青年科学基金(81700676)
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