试论序贯治疗是癌症根治的决胜策略

Sequential Treatment is Key Strategy for Curing Cancer

癌症治疗早期治愈率可上升到90％左右，然而5年乃至更长一点时间，多因屡次复发，而使原治愈水平明显下降。加之中、晚期癌症治疗效果不理想，从而使其总治愈水平难以超过30％左右。究其原因，主要是由于对癌症的生物特性认知欠失和未进行有效的序贯治疗所致。为此，笔者依据癌细胞生物特性将癌症总体根治有计划的分成三级序贯治疗。一级治疗：精确的应用一切抗癌方法的优势，有机的良性综合，使其达到病理形态学阴性；二级治疗：经过有计划连续性序贯治疗，达到分子生物学水平阴性；三级治疗：有效地控制肿瘤复发策源地和减除微小可疑病灶，加强机体免疫功能，提高生活质量，以期还病人一个持久的健康身躯。

The original cure rate of early stage cancer is up to 90% , but declines due to recurrence five or more years after the initial therapy. Furthermore, overall cure rate of middle and advanced stage cancer is only about 30% because of unsatisfactory ef- ficacy. Low cure rate is mainly resulted from insufficient understanding of biological characteristics of cancer and lack of optimal se- quential treatment. Three key stages of cancer sequential treatment are stressed. In the first stage, combination therapy is performed to help morphological recovery. In the second stage, sequential treatment is implemented to promote molecular biological recovery. In the third stage, control of tumor recurrence, elimination of tiny suspicious lesions, enhancement of immune function and improvement of quality of life should be emphasized.