摘要
Mitosis is one of the most fascinating pro- cesses in biology, and is often described as a well-choreographed dance. During mitosis, sister chromatids attach to dynamic microtubules in the mitotic spindle, align and oscillate at the metaphase plate, separ- ate synchronously at the metaphase-ana- phase transition, and are partitioned equally into the two daughter cells. Chromosome missegregation leads to aneuploidy and genomic instability, which can drive tumori- genesis under certain contexts.
