宫颈癌术后化疗患者认知情绪调节与焦虑抑郁水平相关性分析

Investigation on cognitive emotion regulation and anxiety as well as depression in patients with cervical cancer accepting postoperative chemotherapy and their correlation analysis

目的探讨宫颈癌术后化疗患者的认知情绪调节与焦虑、抑郁水平的相关性。方法将2012年5月至2015年5月于秦皇岛市第一医院接受宫颈癌术后化疗的250例患者纳入本研究。采用认知情绪调节问卷中文版调查患者的认知情绪调节情况,采用贝克抑郁自评问卷和贝克焦虑量表调查患者的抑郁和焦虑水平,应用Pearson相关分析检验患者的认知情绪调节与抑郁、焦虑的相关性。结果宫颈癌术后化疗患者中,焦虑症患者占54.4%(136/250),而抑郁症患者占72.0%(180/250)。患者的抑郁程度越重,关于沉思默想、灾难化和责备他人的得分越高,而关于积极调整、关注计划、积极重评的得分越低,差异均具有统计学意义(t=3.979~19.571,均P<0.05)。与无焦虑组相比,焦虑组关于积极调整(t=14.693,P<0.001)的得分较低,而关注计划(t=1.988,P=0.048)、自我安慰(t=3.605,P<0.001)、灾难化(t=16.680,P<0.001)和责备他人(t=5.609,P<0.001)的得分较高,差异均具有统计学意义。患者抑郁与自责、沉思默想、灾难化、责备他人等呈显著正相关(r值分别为0.246、0.378、0.274、0.119,均P<0.05),与关注计划、积极重评呈负相关(r值分别为-0.036、-0.239,均P<0.05)。结论宫颈癌患者的认知情绪调节与抑郁、焦虑密切相关,常应用消极认知情绪调节策略,更易产生抑郁和焦虑。

Objective To investigate the correlation between cognitive emotion regulation and anxiety as well as depression in patients with cervical cancer accepted postoperative chemotherapy. Methods A total of 250 patients with cervical cancer treated by chemotherapy after surgery in the First Hospital of Qinhuangdao during May 2012 to May 2015 were enrolled in this study. The status of cognitive emotion regulation of patients was investigated by the Chinese version of cognitive emotion regulation questionnaire, while the depression and anxiety of patients were evaluated by Beck Depression Inventory and Beck Anxiety Inventory. The Pearson correlation analysis was adopted to test the correlation between cognitive emotion regulation and depression and anxiety. Results Among the patients with cervical cancer accepting postoperative chemotherapy, there were 54.4% （136/250） cases with anxiety and 72% （180/250） cases with depression. With the increasing depression of patients, their scores on meditation, catastrophization and blaming others were getting higher, while their scores on positive adjustment, attention to plans, and active re-evaluation were lower with significant differences （P〈0.05）. Compared with no anxiety group, the patients in anxiety group had lower scores on positive adjustment （t = 14. 693, P〈0. 001） but higher scores on attention to plans （t = 1. 988, P = 0.048）, self-consolation （t=3.605,P〈0.001）, catastrophization （t=16.680, P〈0.001） and blaming others （t = 5.609, P〈0.001） with significant differences （P〈0.05）. The depression in patients was positively correlated with self-criticism, meditation, catastrophization, and blaming others （r value was 0.246, 0. 378, 0. 274 and 0.119, respectively, all P〈0.05）, and negatively correlated with attention to plans and active re-evaluation （r value was -0.036 and -0.239, respectively, all P〈0.05）. Conclusion The cognitive emotion regulation of patients with cervical cancer is closely related to their depression and anxiety. The patients are inclined to adopt negative cognitive emotion regulation strategies, which is easy to make them denressive and anxious.