乳腺癌前哨淋巴结活组织检查术的研究进展

Progress of sentinel lymph node biopsy in breast cancer

乳腺癌是全世界女性最常见的恶性肿瘤之一，严重威胁女性的健康和生命。乳腺癌的外科治疗不断向＂最小最有效＂的模式发展，前哨淋巴结（SLN）活组织检查术（SLNB）在此背景下应运而生。SLNB可免除腋窝淋巴结清扫术（ALND），大大减少了ALND的并发症。近年来，一些临床研究结果提示部分SLN阳性乳腺癌患者即使不接受ALND，其预后也未受到影响，SLN阳性乳腺癌患者是否一定要行ALND的问题有待研究。

Breast cancer is the most common female malignant tumor all over the world, and it seriously threats to women＇s health. As surgical treatment of breast cancer continuously develops to the mode of ＂the smallest and the most effective＂, sentinel lymph node biopsy （SLNB） has emerged. SLNB can avoid axillary lymph node dissection （ALND） and reduce the complications of ALND. In recent years, some clinical research results have showed that the prognosis of sentinel lymph node （SLN） positive breast cancer patients who do not accept ALND can not be affected. The necessity of performing ALND for SLN positive breast cancer patients still needs to be investigated.