新疆农村维吾尔族代谢综合征患病率及其肥胖组分适宜腰围切点的研究

Study on the prevalence rate and optimal waist circumference cut-off points of obesity for the components of metabolic syndrome in Uygur from Xinjiang

目的调查分析新疆农村维吾尔族代谢综合征患病率并探讨其中心性肥胖组分腰围的适宜切点。方法采用分层整群随机抽样的方法，对新疆喀什伽师县18岁及以上常住维吾尔族农村居民3 542人进行问卷调查、体格检查和血生化检测，按照国际糖尿病联盟（IDF）标准，分析男性、女性不同腰围水平和代谢综合征其他组分聚集的关系，并寻找检出两个及以上组分受试者工作特征（ROC）曲线距离最短的腰围切点，作为维吾尔族成人代谢综合征中心性肥胖组分适宜腰围切点。结果按照IDF标准，当男性腰围≥85 cm、女性≥82 cm时，ROC曲线距离最短，以此切点结合其余组分诊断农村维吾尔族代谢综合征患病率为21.3%，男性为19.5%，女性为23.0%，女性高于男性（P〈0.05）。随着腰围升高，维吾尔族人群≥1个、≥2个代谢综合征组分检出率呈增加趋势，OR值明显增高。结论新疆农村维吾尔族居民代谢综合征患病水平高于全国，建议以男性腰围≥85 cm，女性≥82 cm为切点，结合IDF标准其他组分定义作为农村维吾尔族代谢综合征的诊断标准。

ObjectiveTo investigate the prevalence of metabolic syndrome and appropriate cut-off point of waist circumference of abdominal obesity for components of metabolic syndrome in Uygur population in Xinjiang.MethodsA questionnaire-based survey, physical examination, and blood testing were conducted according to cluster random sampling in Uygur residents above 18 years old in Xinjiang. There were 3 542 samples collected, based on the International Diabetes Federation （IDF） standard of metabolic syndrome, the relativities of clustering of metabolic syndrome components and different strata of waist circumference for Uygur were analyzed, and looking for the appropriate cut-off points for identifying two or more components of metabolic syndrome within the shortest distance of receiver operating characteristic （ROC） curve.ResultsAccording to IDF standard, the waist circumference （85 cm for men, 82 cm for women） corresponded to the shortest distance in ROC curve, at these cut-offs of abdominal obesity for component of metabolic syndrome, the prevalences of metabolic syndrome were 21.3%, 19.5% in men, while 23.0% in women, the prevalence of women was higher than that of men （P〈0.05）. The prevalences of ≥1, ≥2 components of metabolic syndrome were shown an increasing trend with the increasing size of waist circumference, and the odds ratio of clustering of metabolic syndrome components were also increased significantly.ConclusionThe prevalence of metabolic syndrome among Xinjiang Uygur population was higher than that of national level. The cut-off points of waist circumference （85 cm for men, 82 cm for women） combining other components definition of IDF standard were recommended for identifying metabolic syndrome of Uygurs.