膀胱内灌注化疗患者焦虑、抑郁调查及影响因素分析

Investigation and analysis of influencing factors ofanxiety and depression in patients with intravesicalperfusion chemotherapy

目的调查膀胱内灌注化疗患者焦虑、抑郁水平及其影响因素。方法采用一般资料调查表、焦虑抑郁量表、自我感受负担量表、社会支持评定量表对148例膀胱内灌注化疗患者进行问卷调查。结果膀胱内灌注化疗患者焦虑、抑郁发生率分别为14．2％（21／148）、20．3％（30／148），与自我感受负担、社会支持及其维度显著相关（P〈0．05），且受病程时间（P=0．002）、宗教信仰（P=0．040）、照顾者功能状态（P=0．009）的影响。结论膀胱内灌注化疗患者焦虑、抑郁发生率可望进一步控制而降低。焦虑方面需要关注患病时间长、情感负担重的患者。而抑郁更多地需要增加其社会支持、降低自我感受负担，并且增加其精神信仰。

Objective To investigate the level of anxiety and depression and its influencing factors in patients with intravesical perfusion chemotherapy. Methods Totally 148 patients with intravesical perfusion chemotherapy were investigated using the Hospital Anxiety and Depression Scale, Self- Perceived Burden Scale and Social Support Rating Scale. Results Among the patients, 14.2% （21/148） and 20.3% （30/148） of them expressed respectively their anxiety and depression, and the incidence of anxiety and depression was significantly correlated with the self-perceived burden, social support and its dimensions （P〈0.05）, in addition to the influence of the course time（P=0.002）, religion（P=0.040）, and thefunctional status of the caregiver（P=0.009）. Conclusions The incidence rate of anxiety and depression in patients with intravesical perfusion chemotherapy is still to be further controlled. Nursing staff should pay attention to patients＂ self-perceived burden, and play an important role in social support in order to reduce the incidence of anxiety and depression.