人参皂苷生物转化的研究进展

Research Progress of Ginsenoside Biotransformation

人参皂苷和稀有人参皂苷是人参属植物的主要活性成分,而稀有人参皂苷具有极高的药理活性,但是在人参属植物中的含量较低,因此通过生物转化得到稀有人参皂苷具有一定的研究价值。目前已有食品级微生物和各种糖苷酶、蜗牛酶等应用到人参皂苷的生物转化中。综述了人参皂苷的种类及功效、酶法和微生物转化法转化人参皂苷的工艺条件和产物,为稀有人参皂苷的大批量工业化生产提供有益的参考。

Ginsenoside and rare ginsenosides are the main active ingredient of Panax species. Rare ginsenosides have very high pharmacological activity,but low content in Panax species. Therefore,it is of research value to obtain rare ginsenosides by biotransformation. At present,there are food-grade microorganisms and various glycosidases,snail enzymes,etc. being applied to ginsenoside biotransformation. This paper reviewed the types and efficacies of ginsenoside,bio-enzymatic and microbial fermentation of ginsenosides biosynthesis products and technological conditions,which provided beneficial references for large quantity industrial production of rare ginsenosides.