基于古代名医治疗心悸病用药配伍规律的文献研究

Literature Study on Compatibility of Medicines in the Treatment of Palpitation by Ancient Famous Doctors

目的:基于数据挖掘古代名医中医药治疗心悸病用药配伍规律的文献研究。方法:将古代名医中医药治疗心悸病的中医方药录入计算机,建立方药数据库,运用统计学方法分析其用药规律。结果:整理古代名医治疗心悸病方剂134首,涉及149味中药,用药总次数1380次;高频次核心药以人参、远志、甘草、茯苓、茯神、麦门冬、当归、生地、朱砂、酸枣仁、熟地等为主;药类以补虚药、安神药、清热药、利水渗湿药等为主。结论:古代名医临证辨治心悸病的方剂主要以补虚药人参、麦门冬、当归、熟地;安神药远志、茯神、朱砂、酸枣仁;清热药甘草、生地;利水渗湿药茯苓配伍组成,人参归脾汤和朱砂安神丸相互合参是辨治心悸病的经典方。

Objective： To study the literature on the compatibility of medications for heart palpitations in traditional Chinese medicine doctors based on data mining. Methods： Traditional Chinese medical prescriptions for the treatment of heart palpitations by famous Chinese medicine practitioners were entered into computers, and a prescription drug database was established. Statistical analysis was used to analyze the drug use patterns. Results： A total of 134 pre- scriptions for the treatment of palpitations were collected from ancient famous doctors. It involves 149 Chinese herbs. The total number of medications is 1380 times; The high frequency medicine is Renshen, Yuanzhi, Ganeao, Fulin, Fushen, Maimendong, Danggui, Shengdi, Zhusha, Suanzaoren, Shudihuang and so on. Among these drugs, the main ones are Buxu medicine, Anshen medicine, Qingre medicine and Lishui Shenshi medicine. Conclusion： The prescrip- tions used by ancient famous doctors to treat cardio-palatitis mainly include tonic drugs Renshen, Maimendong, Dangui and Shudihuang; Anshen medicine： Yuanzhi, Fushen, Zhusha, Suanzaoren; Qingre medicine： Ganeao, Shengdihuang. The diuresis and permeation medicines are made up of compatible ingredients. Renshen Guipi decoction and Zhusha Anshen pills are the classic recipe for differentiating and treating heart disease.