便携式气压治疗仪与低分子肝素预防全髋关节置换术静脉血栓栓塞的护理分析

Nursing analysis of Mobile Compression Device and the Low Molecular Weight Heparin in Prevention of Venous Thromboembolism in Patients Undergoing Total Hip Arthroplasty

目的:探讨全髋关节置换(THA)围手术期应用便携式气压治疗仪(MCD)或应用低分子量肝素(LMWH)对预防血栓和出血发生率的效果评价。方法:纳入200例THA手术的患者,随机分为MCD组(n=100)和LMWH组(n=100)。比较两组患者术后三个月静脉血栓栓塞发生率及住院治疗期间输血量及血红蛋白的变化、大出血事件发生率。结果:住院治疗期间,有6例病人发生大出血事件,均为LMWH组(6%)。术后三个月静脉血栓栓塞的发生率相近,MCD组为5.1%,LMWH组为5.8%。结论:MCD与LMWH在预防VTE方面的效果相当,但前者的大出血发生率显著低于后者。

Objective： To evaluate the effect of the use of mobile compression device therapy （MCD） or low molecular weight heparin （LMWH） in the perioperative period of total hip replacement （THA） to prevent the incidence of throm- bosis and bleeding. Methods： Patients enrolled in 200 THA surgeries were randomly divided into MCD （n=100） and LMWH （n=100） groups. The incidence of venous thromboembolism at three months after surgery, the changes in blood transfusion and hemoglobin during hospitalization, and the incidence of major bleeding events were compared between the two groups. Results： During the hospitalization period, 6 patients experienced major bleeding events, both in the LMWH group （6%）. The incidence of venous thromboembolism was similar in the three months after operation, with 5.1% in the MCD group and 5.8% in the LMWH group. Conclusions： The efficacy of MCD and LMWH in preventing VTE is comparable, but the former has a significantly lower rate of major bleeding than the latter.