显微手术夹闭与血管栓塞术治疗脑动脉瘤的临床效果

Clinical effects of microsurgical clipping and vascular embolization on patients with cerebral aneurysms

目的比较显微手术夹闭、血管栓塞术治疗脑动脉瘤的临床效果。方法选取脑动脉瘤患者60例为研究对象，根据随机数表法及不同差异治疗方式将患者分为研究组与对照组，每组30例。研究组行显微手术夹闭治疗，对照组行血管栓塞术治疗。比较两组临床疗效、住院时间、术后VAS疼痛评分、mRS预后评分、并发症发生率。结果研究组临床治疗总有效率（90.00%）显著高于对照组（66.67%），差异有统计学意义（χ2＝4.812，P〈0.05）。研究组住院时间[（17.46±3.92） d]长于对照组[（9.27±2.08） d]（t＝10.109，P〈0.05），术后VAS评分[（17.46±3.92）分]高于对照组[（2.78±1.03）分]（P〈0.05）。两组预后mRS评分比较差异未见统计学意义（P〉0.05）。研究组术后并发症发生率（13.33%）低于对照组（36.67%），差异有统计学意义（χ2＝4.356，P〈0.05）。结论与血管栓塞术比较，显微手术夹闭治疗脑动脉瘤总有效率更高，并发症更少，但术后疼痛程度较高，住院时间较长，而两者远期预后相当。临床治疗应根据动脉瘤情况行综合考量，以选择合适有效的治疗方式。

ObjectiveTo compare the clinical effects of microsurgical clipping and endovascular embolization on cerebral aneurysms. MethodsSixty patients with cerebral aneurysm were selected as the research objects. According to the random number table method and treatment methods, the patients were divided into study group and control group, with 30 cases in each group. The study group underwent microsurgery clipping treatment, and the control group underwent endovascular embolization treatment. The clinical efficacy, length of stay, postoperative VAS pain score, mRS prognosis score and complication rate were compared between the two groups.ResultsThe total effective rate of clinical treatment in the study group （90.00%） was significantly higher than that of the control group （66.67%）, the difference was significant （χ2=4.812, P〈0.05）. The hospitalization time [（17.46±3.92） d] in the study group was longer than that in the control group [（9.27±2.08） d] （t=10.109, P〈0.05）, and the postoperative VAS score [（17.46±3.92） score] was higher than that of the control group [（2.78±1.03） score] （P〈0.05）. There was no significant differences between the two groups in the mRS score of patients （P〉0.05）. The incidence of postoperative complications in the study group （13.33%） was lower than that of the control group （36.67%）, and the difference was significant （χ2=4.356, P〈0.05）.ConclusionsCompared with vascular embolization, the total effective rate of the microsurgical clipping is higher and has less complications, but the postoperative pain is higher, the hospitalization time is longer, and the long-term prognosis is same as vascular embolization. The clinical treatment should be comprehensively considered according to the condition of the aneurysm, so as to select a suitable effective treatment mode.