两种微柱凝胶卡检测孕妇血清抗体效价的比较

Comparative Analysis on Domestic and Import Micro-Column Gel Cards for Detction of Maternal Antibody Titers

目的:探讨进口和国产微柱凝胶卡检测孕妇血清抗体差异及符合性。方法:采用两种微柱凝胶卡对2016年4月至2016年6月东凤人民医院接诊的200例妊娠≥16周的O型Rh(D)阳性孕妇进行血清抗体效价检测,以进口微柱凝胶卡结果为标准与国产微柱凝胶卡进行比较分析。结果:国产和进口微柱凝胶卡在抗A效价检测中,进口微柱凝胶卡阳性检出率为73.5%,国产微柱凝胶卡阳性检出率为65.5%;抗B效价检测中,进口微柱凝胶卡阳性检出率为67.0%,国产微柱凝胶卡阳性检出率为63.0%。以进口微柱凝胶卡结果为标准,国产微柱凝胶卡抗A效价的灵敏度为87.8%,特异度为96.2%。国产微柱效卡抗B效价的灵敏度为91.9%,特异度为98.5%。结论:进口微柱凝胶卡的阳性率比国产微柱凝胶卡略高,组间比较,差异无统计学意义(P>0.05)。

Objective To compare the difference and coincidence of serum antibodies between imported and domestic microcolumn gel cards in pregnant women. Methods Two kinds of microcolumn gel cards were used to test the serum antibody titer of 200 cases of O-type pregnant women admitted to Dongfeng People＇s Hospital from April 2016 to June 2016. The results of imported microcolumn gel cards as standard and domestic microcolumn gel card for comparative analysis. Results Domestic and imported micro-column gel cards in the detection of anti-A titer, the positive rate of imported micro-column gel card was 73.5%, the detection rate of domestic micro-column gel card was 65.5%, and the anti-B titer was detected. The positive rate of imported micro-column gel card was 67%, and the positive rate of domestic micro-column gel card was 63%. Taking the results of imported microcolumn gel cards as the standard, the sensitivity of domestic microcolumn gel card anti-A titer was 98.5% and the specificity was 73.9%. The sensitivity of domestic microcolumn anti-B titer was 99.2% and the specificity was 85.7%. Conclusion The positive rate of imported microcolumn gel cards was slightly higher than that of domestic microcolumn gel cards. There was no significant difference between the two groups （P 〉 0.05）.