肥胖的药物、手术和介入治疗

Pharmacotherapy, surgery and intervention treatment in obesity management

全球肥胖人数迅猛增加,肥胖相关并发症也逐渐出现。肥胖治疗主要目的除了减轻体质量,还包括减少肥胖相关并发症的出现和避免体质量的反弹。近年来,奥利司他等多种可长期治疗肥胖的药物陆续进入临床,减重手术和胃左动脉栓塞术也开始兴起。本文系统综述肥胖的药物治疗、手术和介入治疗进展及其临床评价。

Obesity has rapidly increased and the obesity-related comorbidities have been emerged as well. The treatment for obesity is not only aimed to lose weight, but also to reduce the occurrence of obesity-related comorbidities and to avoid regaining weight. Recently, the orlistat and other obesity drugs have been used in clinic successively. However, the bariatric surgery and left gastric artery embolization have been expanded over recent years alternatively. This review describes the pharmacotherapy, surgery and interventional treatment for the management of obesity.