支气管扩张症临床表型的研究进展

Progress of clinical phenotypes of bronchiectasis

支气管扩张症具有较大的异质性，需要个体化的治疗。临床表型的分类是个体化治疗的前提，近年来，支气管扩张症合并慢性阻塞性肺疾病（COPD）已成为重要的临床表型，聚类分析法在支气管扩张症的临床表型分类中逐渐显示出独特的优势，新的支气管扩张症评分系统层出不穷。本综述回顾了近年有关支气管扩张症临床表型的研究进展。

Bronchiectasis is a heterogeneous disease with various etiology and clinical manifestation. Thus, the treatment should be individualized and based on the clinical phenotypes of bronchiectasis. In recent years, the coexistence of bronchiectasis and chronic obstructive pulmonary disease （COPD） has been regarded as a distinct phenotype of great prognostic value, and cluster analysis has been proposed to examine phenotypic heterogeneity in patients with bronchiectasis. Besides bronchiectasis severity index （BSI） and FACED （F： forced expiratory volume in 1s% predicted, A： age, C： chronic colonisation by Pesrdomonas aeruginosa, E：radiological extension, D：dyspnea） score, new scoring systems of bronchiectasis are emerging. In this review, we studied recent literature on the clinical phenotypes of bronchiectasis.