应用超声探讨下肢动脉硬化与冠心病的相关性

Investigating correlation between lower extremity arteriosclerosis and coronary heart disease by ultrasound

目的应用超声探讨下肢动脉硬化与冠心病的关系。方法选取104例冠心病确诊患者为研究组，根据冠状动脉病变程度分为多支病变组（60例）和单支病变组（44例）；同时选取同期体检者200名作为对照组。观察研究组与对照组患者下肢动脉粥样硬化硬化程度，包括内中膜厚度和有无斑块形成。结果研究组下肢动脉硬化斑块发生率高于对照组（P〈0．05）。研究组下肢动脉硬化斑块发生率随冠心状动脉病变程度增加而增加，其中多支病变组下肢动脉硬化斑块发生率高于单支病变组（P〈0．05）。结论下肢动脉硬化与冠心病存在一定相关性，其对冠心病的诊断及冠状动脉病程发展的预测具有重要意义。

Objective To investigate the relationship between lower extremity arteriosclerosis and coronary heart disease by ultrasound. Methods A total of 104 patients with coronary heart disease were selected as study group, and then were divided into multivessel disease group （60 cases） and one- vessel lesion group （44 cases） ; and 200 patients who underwent physical examination during the same period were selected as control group. The degree of lower extremity atheroselerosis of study group and control group was observed, including intima-media thickness and plaque formation. Results Compared with control group, the incidence of atherosclerotic plaque in lower extremity of study group was significantly higher （ P 〈 0. 05 ）. At the same time, the incidence of atherosclerotic plaque in the lower extremity of study group has positive correlation with the degree of coronary artery disease ; and the incidence of atherosclerotic plaque in lower extremity in multivessel disease group was significantly higher than that in one-vessel lesion group （ P 〈 0.05 ）. Conclusions Lower extremity arteriosclerosis has a certain correlation with coronary heart disease and it plays an important role in diagnosis of coronary heart disease and the prediction of progress of coronary artery disease.