孕妇围产期B族链球菌感染危险因素的Logistic分析

Logistic regression analysis on risk factors of group B streptococcal infection in pregnant women during perinatal period

目的探讨孕妇围产期B族链球菌感染的危险因素，为防治B族链球菌感染提供参考依据。方法回顾性分析住院分娩的576例孕妇的临床资料，均于妊娠35～37周进行B族链球菌培养测定，根据有无B族链球菌感染分为感染组和未感染组。比较两组临床资料，并通过多因素Logistic分析导致孕妇围产期B族链球菌感染的危险因素。结果576例孕妇中，47例出现B族链球菌感染（8．16％）；感染组流产史、生殖道感染比例均高于未感染组，差异均有统计学意义（P均〈0．05）；多因素Logistic回归分析结果显示，生殖道感染、流产史为影响B族链球菌感染发生的独立危险因素（P〈0．05）；感染组早产、宫内感染发生率高于未感染组，差异均有统计学意义（P均〈0．05）。结论生殖道感染、流产史为孕妇围产期B族链球菌感染的独立危险因素，应加强女性生殖健康及避孕措施宣教，以减少孕产妇B族链球菌感染的发生。

Objective To investigate the risk factors of group B streptococcal infection in pregnant women during perinatal period, to provide reference for prevention and treatment of group B streptococcal infection. Methods The clinical data of 576 pregnant women were retrospectively analyzed, and group B strep- tococcal was cultured and measured at 35 -37 weeks of pregnancy, and all patients were divided into infected group and uninfected group according to whether they were infected with group B streptococcus or not. The clinical data of the two groups were compared, and risk factors of group B streptococcal infection in perinatal period were analyzed by multivariate unconditional Logistic regression analysis. Results In 576 pregnant women, 47 cases （8. 16% ） were infected with the group B streptococcal. The proportion of abortion and reproductive tract infection in infection group were significantly higher than those in uninfected group, the differences were statistically significant （ all P 〈 0. 05）. Multivariate Logistic regression analysis showed that reproductive tract infection and abortion history were independent risk factors for group B streptococcal infection （P 〈 0. 05）. The incidences of premature and intrauterine infection in infection group were significantly higher than those in uninfected group, the difference was statistically significant （P 〈0. 05）. Conclusions The reproductive tract infection and abortion history are the independent risk factors of group B streptococcal infection, and the female reproductive health and contraception education should be strengthened to reduce the incidence of group B streptococcal infection.