摘要
目的探讨原发性痛风患者治疗依从性及达标率情况,为临床诊治工作提供参考依据。方法采用简单随机抽样法抽取2015年6月-2016年6月北京朝阳医院门诊就诊的痛风间歇期患者100例,均已接受过降尿酸治疗的,病程〉6个月,自愿加入本调查研究。采用改良的中文版风湿病治疗依从性问卷(CCQR)调查分析其治疗依从性及降尿酸治疗达标率。结果共收回有效问卷共84份。84例痛风患者中治疗依从性高者46例(54.8%),治疗依从性差者38例(45.2%)。治疗依从性高组CCQR为(73.48±15.62)分,治疗依从性低组CCQR为(48.37±10.96)分,差异有统计学意义(t=8.352,P〈0.001)。治疗依从性高组与依从性低组在文化程度、个人月收入、家族史、有无医疗保险和降尿酸药物类型方面差异无统计学意义(P〉0.05)。治疗依从性高组患者痛风病程明显短于治疗依从性低组[(6.12±1.79)年比(13.24±4.56)年,t=9.731,P〈0.001],差异有统计学意义。治疗依从性与病程、发作频率有关,差异有统计学意义(P〈0.05)。治疗依从性高组患者降尿酸治疗达标率为35例(76.1%),明显高于治疗依从性低组14例(36.8%),差异有统计学意义(χ2=13.186,P=0.0003)。两组血尿酸平均水平分别为(369.82±35.67)μmol/L比(497.46±63.49)μmol/L,差异有统计学意义(t=11.606,P〈0.001)。结论临床上需加强痛风患者健康教育,尤其反复发作、病程较长患者对疾病认知情况的管理,提高其治疗依从性,从而提高降尿酸治疗达标率。
Objective To investigate the treatment compliance and uric acid control rate in patients with primary gout. Methods One hundred primary gout patients with disease duration 〉 6 months treated in our hospital from June 2015 to June 2016 were enrolled in the study. The treatment compliance and disease control rate were evaluated with revised Chinese Compliance Questionnaire-Rheumatology (CCQR). Results Eighty four valid questionnaires was recovered for analysis. Among 84 patients there were 46 cases of high compliance (54. 8% ) and 38 cases of poor compliance (45. 2% ). The CCQR score in high compliance group was significantly higher than that in poor compliance group (73.48 ± 15.62 vs. 48.37 ±10.96, t =8. 352 ,P 〈0. 001 ). There were no significant differences in education level, personal income, family history, health insurance and type of uric-acid-lowering drugs between high compliance group and low compliance group ( P 〉 0.05 ). The duration of gout was shorter in high compliance group than that in low compliance group [ (6.12±1.79)y vs. (13.24±4.56) y, P 〈 0. 001 ]. The uric acid control rate in high compliance group was higher than that in poor compliance group (76.1% vs. 36.8% , χ2 = 13. 186,P = 0.0013 3 ) ; and the serum uric acid levels were( 369.82 ±35.67 ) μ mol/L and (497.46 ± 63.49 ) μ moL/L in two groups, respectively ( t = 11. 606, P 〈 0. 001 ). Conclusion It is necessary to strengthen health education for gout patients to improve the treatment compliance and to achieve the high uric acid control rate.
作者
孟娟
袁晓旭
明昕
路跃武
Meng Juan, Yuan Xiaoxu, Ming Xin, Lu Yuewu(Department of Rheumatology and Immunology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, Chin)
出处
《中华全科医师杂志》
2018年第4期281-285,共5页
Chinese Journal of General Practitioners
关键词
痛风
病人依从
问卷调查
Gout
Patient compliance
Questionnaires