老年2型糖尿病合并骨质疏松症相关因素分析

目的对老年2型糖尿病（T2DM）患者合并骨质疏松症（OP）的相关因素进行研究，为提高诊断提供理论依据。方法选取本院72例2型糖尿病患者，检测患者的年龄、性别、糖尿病病程、身高、体重、腹围、清晨空腹血糖（FPG）、血钙、血磷、碱性磷酸酶（ALP）、糖化血红蛋白（HbA1C）及骨密度（BMD）的水平，并根据骨密度分为OP组和非OP组，进行组间差异分析和相关性分析。结果OP组年龄、体重指数（BMI）、病程、HbA1C与非OP组比较差异有统计学意义（P〈0．05），而FPG、ALP、腹围、血钙、血磷的差异无统计学意义（P〉0．05），老年T2DM患者的BMD与年龄、病程、HbA1C呈负相关，与BMI呈正相关，与FPG、ALP、腹围、血钙、血磷无关性。结论病程长、高龄、血糖控制差、体重指数低的老年T2DM患者更容易合并OP。

Objective To explore the influence of elderly type 2 diabetic patients （ T2DM ） with osteoporosis-related factors. Methods According to bone mineral density （ BMD ） , 72 patients with type 2 diabetes mellitus were divided into osteoporosis （ OP ） group and non-OP group. The age, sex, duration of diabetes, height, weight, abdominal circumference, body mass, fasting plasma glucose （FPG） , serum calcium, serum phosphorus, alkaline phosphatase （ ALP ） , glycosylated hemoglobin （ HbA1C ） were compared between the two groups. The correlation was analyzed. Results There were significant differences in the age, body mass index （ BMI ） , duration of diabetes, HbA1C between OP group and non-OP group （P〈0.05） . The BMD was negatively correlated with the age, duration of diabetes, HbA1 C, but positively correlated with BMI in elderly patients with T2DM.There was no correlation between BMD and FPG, ALP, abdominal circumference, serum calcium, serum phosphorus. Conclusion The risk factors for osteoporosis in elderly patients with T2DM including old age, loss BMI, long duration of diabetes and high HbA 1 C levels.