妊娠期肝衰竭母儿预后的评估

Prognostic assessment of mother and infant in live failure during pregnancy

妊娠期肝衰竭病情凶险,孕妇和胎儿死亡率高。乙型肝炎病毒感染和妊娠期急性脂肪肝是导致我国妊娠期肝衰竭的主要原因,有效的病情评估和及时终止妊娠是改善母儿预后的主要手段。终末期肝病模型评分、肝功能CTP评分和Swansea标准对急慢性肝衰竭和妊娠期急性脂肪肝预后有一定的评估价值,但尚需在临床工作中进一步探讨。

Live failure during pregnancy often evolves critically and carries out high maternal-fetus mortality. Infection of hepatitis B virus and acute fatty liver of pregnancy（ AFLP） are the most common causes of liver failure during pregnancy in China. Prognosis can be improved with effective evaluation of illness state and timely termination of pregnancy. The model for end-stage liver disease（ MELD） scoring system,Child-Turcotte-Pugh（ CTP） scoring system of liver function and Swansea criteria can be used to predicting the prognosis of acute-chronic hepatitis B liver failure and AFLP,but it should be further explored in clinical work.