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β-catenin、B7-H3蛋白表达与脑胶质瘤患者病理分级的关联性分析 被引量:1

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摘要 目的探讨β-链蛋白(β-catenin)、共刺激分子(B7-H3)蛋白表达与脑胶质瘤患者病理分级的关联性。方法选取周口市中心医院脑胶质瘤患者37例为观察组,另选同期健康体检者35例为对照组,均行β-catenin、B7-H3蛋白检测,并比较两组β-catenin、B7-H3水平,分析β-catenin、B7-H3蛋白表达与脑胶质瘤患者病理分级的关联性。结果观察组β-catenin阳性表达率为78.38%(29/37)、B7-H3蛋白阳性表达率为62.16%(23/37)高于对照组0.00%(0/35)、16.21%(6/35),差异有统计学意义(P<0.0 5);β-catenin、B7-H3蛋白表达与脑胶质瘤患者病理分级有关(P<0.05)。结论β-catenin、B7-H3蛋白于脑胶质瘤组织中均呈现异常高表达状态,二者表达水平均与脑胶质瘤患者病理分级有关。
作者 宋艳芳
出处 《首都食品与医药》 2018年第7期18-18,共1页 Capital Food Medicine
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