全凭静脉麻醉与吸入七氟烷对老年患者术后认知功能影响的比较

目的探讨全凭静脉麻醉与吸入七氟烷对老年患者术后认知功能的影响。方法选取我院收治的120例老年手术患者为研究对象,以麻醉方式异同分为全凭静脉组(n=60,全凭静脉麻醉)和吸入组(n=60,吸入七氟烷),对两组患者苏醒时间、术后认知功能进行观察对比。结果全凭静脉组苏醒时间(17.15±6.85)min、听从指令时间(10.45±2.55)min、定向力恢复时间(11.68±2.32)m i n、P O C D发生率2 3.3 3%均明显低于吸入组[(3 1.0 4±9.8 6)m i n、(13.30±2.70)min、(15.27±2.63)min、41.67%],且术后各时间段MMSE评分明显高于吸入组,P<0.05。结论采用全凭静脉麻醉的方式对老年手术患者术后认知功能影响更小,且患者苏醒时间短,有利于术后迅速恢复,值得临床应用。

Objective To investigate the effect of intravenous anesthesia and inhalation of sevoflurane on cognitive function in elderly patients. Methods 120 elderly patients were selected as the subjects, and the anesthesia was divided into all the intravenous group （n=60,total intravenous anesthesia） and inhalation group （n=60,inhaled sevoflurane） The awakening time and postoperative cognitive function of the two groups were observed and compared. Resu Its The recovery time （11.68 ± 2.32） min and the incidence of cognitive impairment were significantly lower than those in the inhalation group （17.15± 6.85） rain, （ 10.65 ± 2.55 ） min, （31.04±9.86） min, （13.30±2.70） min, （15.27 ± 2.63） min, 41.67%, and MMSE scores were significantly higher in the respective groups than in the inhalation group （P〈0.05）. Conc I us i on The effect of fulltime intravenous anesthesia on the cognitive function of the elderly patients is less, and the recovery time is short, which is beneficial to the rapid recovery after operation and is worthy of clinical application.