依达拉奉注射液、醒脑静注射液联合氯吡格雷片治疗急性脑梗死40例疗效分析

Analysis of efficacy of edaravone injection, Xingnaojing injection combined with clopidogrel tablets in the treatment of 40 cases acute cerebral infarction

目的探讨针对急性脑梗死患者采用依达拉奉、醒脑静联合氯吡格雷治疗的临床疗效。方法 80例急性脑梗死患者,随机分为对照组与观察组,每组40例。对照组给予依达拉奉联合氯吡格雷治疗,观察组给予依达拉奉、醒脑静联合氯吡格雷治疗。比较两组的临床疗效。结果治疗前两组神经功能缺损程度评分比较差异无统计学意义(P>0.05);治疗7、14 d两组神经功能缺损程度评分均低于本组治疗前,且观察组均低于对照组,差异均具有统计学意义(P<0.05)。观察组治疗总有效率为95.00%,高于对照组的77.50%,差异具有统计学意义(P<0.05)。结论在急性脑梗死治疗中采用依达拉奉、醒脑静联合氯吡格雷方案可有效改善患者症状,减轻神经功能缺损程度,临床治疗价值较高。

Objective To discuss the clinical efficacy of edaravone injection, Xingnaojing injection combined with clopidogrel tablets in the treatment of acute cerebral infarction. Methods A total of 80 acute cerebral infarction patients were randomly divided into control group and observation group, with 40 cases in each group. The control group was treated with edaravone combined with clopidogrel, and the observation group was treated with edaravone combined with Xingnaojing. The clinical efficacy in two groups was compared. Results Before treatment, both groups had no statistically significant difference in neurological deficit degree score（P〉0.05）. After 7 and 14 d of treatment, both groups had lower neurological deficit degree score than before treatment, and the observation group was lower than the control group. Their difference was statistically significant（P〈0.05）. The observation group had higher total treatment effective rate as 95.00% than 77.50% in the control group, and the difference was statistically significant（P〈0.05）. Conclusion Combination of edaravone, Xingnaojing and clopidogrel can effectively improve the symptoms of patients with acute cerebral infarction and relieve their neurological deficit degree with high clinical treatment value.