碳纳米材料在胃癌治疗中的应用进展

Application advances of carbon nanomaterial in therapy for gastric cancer

目的了解碳纳米材料在胃癌治疗中的应用现状。方法对国内外有关碳纳米材料应用于胃癌治疗中的文献进行复习并进行综述。结果碳纳米材料作为淋巴结示踪剂在胃癌淋巴结中染色明显,示踪效果好,能够提高淋巴结的检出数量及转移淋巴结的检出率。碳纳米材料作为化疗药物载体,可以提高淋巴结内药物的浓度从而抑制胃癌细胞的转移。结论碳纳米材料能够为胃癌的治疗提供有效帮助,但其是否能改善胃癌患者的预后仍有待研究。

Objective To summarize application status of carbon nanomaterial in gastric cancer therapy. The relevant literatures about the application of the carbon nanomaterial in the gastric cancer were reviewed. Results The carbon nanomaterial was as a lymph tracer with good effects for dying and tracing, which could improve the number of lymph nodes and the detection rate of metastasis lymph nodes. As be made as a transition of chemotherapy drugs, the carbon nanomaterial could improve the concentration of the drug in the lymph node, then inhibit the gastric cancer cell to spread. Conclusion Carbon nanomaterial provides an effective help in treatment for gastric cancer, but whether it could improve prognosis of patient with gastric cancer remains to be studied.