围绝经期抑郁症的中医病机和证型研究

Research on Traditional Chinese Medicine Pathogenesis and Syndrome Type of Perimenopausal Depression

目的期望通过较大样本临床资料,研究围绝经期抑郁症的病机和证型分布情况,为进一步的临床诊治提供依据。方法收集南京地区385例围绝经期抑郁症病例,进行问卷调查,量表分析。结果本研究中的主要证型依次为心肾不交兼有肝郁型、肝郁肾虚型、肾虚型、肝郁气滞型和心肾不交型。结论该疾病的发生发展和肾、肝、心、脾多脏关系密切,并以肾虚肝郁和心肾不交兼夹肝郁为主要证型。

Objective Through large scale clinical information,to study the pathogenesis and syndromes of perimenopausal depression,and to provide the basis for further diagnosis and treatment. Methods Collecting 385 patients with perimenopausal depression cases in Nanjing area,questionnaire and scale of analysis were carried out. Results The main type in this study were heart-kidney imbalance and liver depression syndrome,kidney deficiency with liver stagnation,kidney deficiency,liver qi stagnation and heart-kidney imbalance. Conclusion Development and progression of the disease is closely related to kidney,liver,heart,spleen,heart-kidney imbalance and liver depression syndrome,kidney deficiency with liver stagnation as the main type.