TG/HDLC值与ACS患者经皮冠状动脉介入治疗术后院内主要不良心血管事件的相关性

The relationship between TG/HDLC ratio and in-hospital major adverse cardiac events in acute coronary syndrome after percutaneous coronary intervention

目的研究血清TG/HDLC值与急性冠状动脉综合征（ACS）患者经皮冠状动脉介入治疗（PCI）术后院内主要不良血管事件（MACE）的相关性。方法选取2014年1月至2015年1月洛阳市中心医院接受PCI治疗的患者214例,应用多因素Logistic回归分析TG/HDLC是否可作为ACS患者发生院内主要不良血管事件的独立危险因素,根据TG/HDLC值分为高TG/HDLC值组（66例）、中TG/HDLC值组（74例）、低TG/HDLC值组（74例）,对三组患者院内发生主要不良心血管事件的风险进行比较。结果多因素Logistic回归模型中,通过校正年龄、性别、吸烟史、高血压病史、糖尿病史和冠状动脉狭窄程度,Log TG/HDLC值是ACS患者院内主要不良血管事件的独立危险因素（OR=6.90,95%CI为1.90～25.06,P=0.003）,高TG/HDLC值组发生不良心血管事件风险是低TG/HDLC值组的3.27倍。结论 TG/HDLC值对ACS患者PCI术后院内主要不良心血管事件的发生具有重要的预测价值。

Aim To explore the relationship between the TG/HDLC ratio and in-hospital MACE in acute coronary syndrome（ ACS） after percutaneous coronary intervention（ PCI）. Methods A total of 214 ACS patients receiving primary PCI admitted in our hospital from January 2014 to January 2015 were enrolled in this study. Multivariate analysis was conducted to assess whether TG/HDLC ratio was the independent predictor for in-hospital MACE occurrence.And the subjects were divided into three groups according to TG/HDLC ratio. The differences OR of in-hospital MACE between low TG/HDLC ratio group（ n = 66）,middle TG/HDLC ratio group（ n = 74） and high TG/HDLC ratio group（ n =74） were compared. Results After adjusting for age,smoking,hypertension,diabetes,and severity of angiographic coronary disease by the multivariate Logistic regression model,the Log TG/HDLC ratio was the independent risk factor for in-hospital MACE（ OR = 6.90,95%CI was 1.90 ~ 25.06,P = 0.003）. ACS patients with the higest tertile of TG/HDLC ratio exhibited multivariable-adjusted OR of 3.27 for in-hospital MACE compared with ACS patients with the lowest quartile of TG/HDLC ratio. Conclusion The TG/HDLC ratio is a powerful independent predictor of MACE.